Rabeprazole is a generic medication used to manage various gastrointestinal conditions, including Gastro-Oesophageal Reflux Disease (GORD) and stomach ulcers, as part of the proton pump inhibitors (PPIs) category. It functions by decreasing stomach acid production, thus easing symptoms like acid reflux and heartburn. Additionally, it helps heal oesophageal damage and prevents the formation of stomach ulcers.

Moreover, Rabeprazole is prescribed for Zollinger-Ellison syndrome, a condition characterized by excessive stomach acid production due to a pancreatic tumour, and it is effective in treating H. pylori infections in individuals with peptic ulcer disease.

For further information, patients can refer to the Rabeprazole patient information leaflet.

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Rabeprazole functions by decreasing the production of stomach acid. It targets conditions like Gastro-Oesophageal Reflux Disease (GORD), characterised by symptoms such as acid reflux, heartburn, stomach ulcers, and inflammation of the oesophagus and gullet.

Acting in a manner consistent with other proton pump inhibitors (PPIs), Rabeprazole inhibits the operation of the proton pump—a cellular mechanism in the stomach lining responsible for acid production. By curtailing acid production, it alleviates GORD symptoms, aids in healing ulcers in the stomach lining, and prevents damage to the oesophagus.

Furthermore, Rabeprazole is available as a delayed-release tablet, designed to release the medication in the intestine rather than the stomach, where it could be neutralized by stomach acid. This delivery method enhances Rabeprazole's efficacy over an extended period, as it allows for more effective binding to the proton pump.

Rabeprazole comes in tablet form with dosages of either 10 mg or 20 mg. For managing GORD symptoms, including heartburn and acid reflux, the typical daily dosage ranges from 10 to 20 mg. A daily dose of 20 mg is recommended for the treatment of stomach ulcers.

Swallow the tablet whole. Don’t crush or chew it.

Side effects that occur in more than 1 out of 100 individuals are considered common. If these side effects persist after completing your course of Rabeprazole, it's crucial to consult your GP.

Common adverse effects include:

• Headaches
• Diarrhoea
• Nausea and vomiting
• Constipation
• Stomach pain or gas.

Regarding serious side effects, their frequency varies. Contact your GP immediately if you experience:

• Joint pain and unusual skin changes, particularly on sun-exposed areas, like a red, raised rash on your arms that may spread, blisters, or a red rash across your cheeks and nose.
• Continuous stomach pain that intensifies.
• Yellowing of the skin or the whites of your eyes
• Dark-coloured urine
• Pain during urination
• Reduced urination
• Lower back pain
• Swelling in the ankles
• Rash
• Fever
• Recurrent infections, such as a sore throat or high fever
• Mouth or throat ulcers.

Most people who take PPIs don’t get any side effects from them. For a complete list of possible side effects, check the leaflet that comes with your treatment.

https://pubmed.ncbi.nlm.nih.gov/11772142/

Rabeprazole is often recommended as a primary treatment option for managing GORD symptoms and its long-term maintenance. Research has validated its efficacy in alleviating GORD symptoms and curing stomach ulcers. In a comparative study between rabeprazole and a placebo, rabeprazole proved to be markedly superior in treating GORD symptoms, particularly in controlling acid reflux.

Omeprazole is also recognized for its effectiveness in treating GORD. Comparative studies have demonstrated that Rabeprazole's performance is on par with omeprazole, achieving a symptom healing rate of 87%.

https://pubmed.ncbi.nlm.nih.gov/9590413/

https://pubmed.ncbi.nlm.nih.gov/11318537/

Living with GORD can be challenging, which is why we aim to streamline the treatment process for you. By consulting with our knowledgeable clinicians, you'll be presented with several treatment options tailored to your needs; simply select the one you prefer. You can expect your medication to arrive directly at your doorstep, possibly as soon as the next day.

Our flexible subscription service allows you to manage your medication deliveries according to your schedule. If you ever need to make changes, you can easily cancel, pause, or adjust your preferences through your account. We're committed to supporting you throughout your treatment journey and will check in to see how you're progressing. Feel free to reach out at any time with questions or for further assistance.